Cyp33 binds AU-rich RNA motifs via an extended interface that competitively disrupts the gene repressive Cyp33-MLL1 interaction in vitro.

Cyp33 is an essential human cyclophilin prolyl isomerase that plays myriad roles in splicing and chromatin remodeling.In addition to a canonical cyclophilin (Cyp) domain, Cyp33 contains an RNA-recognition motif (RRM) domain, and RNA-binding triggers proline isomerase activity.One prominent role for Cyp33 is through a direct interaction with the mix

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Probiotics and Atopic Dermatitis: An Overview

Atopic dermatitis (AD) is a common, recurrent, chronic inflammatory skin disease that is a cause of considerable economic and social burden.Its prevalence varies substantially among different countries with an incidence rate Twin Coverlet Set proclaimed to reach up to 20% of children in developed countries and continues to escalate in developing na

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